SCHEMBL6239503

SCHEMBL6239503

N#Cc1nc(NCC2CCCCC2)nc(N2CCCCC2)n1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTSB P07858 6/20 0.57
CTSK P43235 6/20 0.57
CTSS P25774 5/20 0.57
CTSL P07711 5/20 0.57
ALDH1A1 P00352 3/20 0.54
MAPK1 P28482 2/20 0.54
GALR3 O60755 2/20 0.54
RAB9A P51151 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
NPC1 O15118 1/20 0.54
TP53 P04637 1/20 0.54
KDM4E B2RXH2 1/20 0.49
HSD17B10 Q99714 1/20 0.49
LMNA P02545 2/20 0.47
GAA P10253 1/20 0.47
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6238836 0.90 KDM4E (0.58) CTSBCTSKCTSSCTSLALDH1A1
SCHEMBL14504385 0.86 MEN1 (0.54) ALDH1A1SMN1; SMN2LMNAGAATSHR
SCHEMBL6235821 0.80 CTSS (0.81) CTSBCTSKCTSSCTSLALDH1A1
SCHEMBL6259447 0.80 CTSS (0.81) CTSBCTSKCTSSCTSLALDH1A1
SCHEMBL6239841 0.78 CTSS (0.74) CTSBCTSKCTSSCTSLALDH1A1
SCHEMBL6269004 0.77 ALDH1A1 (0.55) CTSBCTSKCTSSCTSLALDH1A1
SCHEMBL6241051 0.77 CTSS (0.76) CTSBCTSKCTSSCTSLALDH1A1
SCHEMBL6266358 0.74 ALDH1A1 (0.96) CTSBCTSKCTSSCTSLALDH1A1
SCHEMBL6235670 0.74 ALDH1A1 (0.96) CTSBCTSKCTSSCTSLALDH1A1
SCHEMBL6236491 0.73 CTSK (1.00) CTSBCTSKCTSSCTSLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005011703-A1 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES AKZO NOBEL N.V. (NL) 2005-02-10 WO disclosed