Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.63 |
| ▸ | PTGES | O14684 | 2/20 | 0.56 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239571 | 0.83 | MAOB (0.58) | MAOBPTGESCYP26B1FFAR1ESR1 | |
| SCHEMBL11806213 | 0.79 | MAOB (0.57) | MAOBPTGESCYP26B1FFAR1ESR1 | |
| SCHEMBL11822400 | 0.79 | MAOB (0.57) | MAOBPTGESCYP26B1FFAR1ESR1 | |
| SCHEMBL3983367 | 0.77 | MAOB (1.00) | MAOBFFAR1ESR1ESR2MAOA | |
| SCHEMBL3626409 | 0.77 | MAOB (0.68) | MAOBFFAR1ESR1ESR2MAOA | |
| SCHEMBL1601919 | 0.76 | MAOB (0.54) | MAOBPTGESCYP26B1FFAR1ESR1 | |
| SCHEMBL2149692 | 0.76 | MAOB (0.66) | MAOBPTGESFFAR1ESR1ESR2 | |
| SCHEMBL11804512 | 0.75 | RELA (0.53) | MAOBPTGESCYP26B1FFAR1ESR1 | |
| SCHEMBL11804481 | 0.74 | MAOB (0.51) | MAOBPTGESCYP26B1FFAR1ESR1 | |
| SCHEMBL11804485 | 0.74 | MAOB (0.51) | MAOBPTGESCYP26B1FFAR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385505-A2 | ACNE TREATMENT | Zouboulis, Christos (DE) | 2004-02-04 | — | — | EP | claimed |
| WO-2002089791-A2 | ACNE TREATMENT WITH LIPOOXIGENASE INHIBITORS | ZOUBOULIS CHRISTOS C (DE) | 2002-11-14 | — | — | WO | claimed |
| EP-1385505-A2 | ACNE TREATMENT | Zouboulis, Christos (DE) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002089791-A2 | ACNE TREATMENT WITH LIPOOXIGENASE INHIBITORS | ZOUBOULIS CHRISTOS C (DE) | 2002-11-14 | — | — | WO | disclosed |