Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.66 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068959 | 0.85 | MAOB (0.70) | FFAR1FFAR4MAOBSMN1; SMN2RAB9A | |
| SCHEMBL9491438 | 0.83 | FFAR1 (0.68) | FFAR1FFAR4MAOB | |
| SCHEMBL1745006 | 0.83 | FFAR1 (0.73) | FFAR1FFAR4PPARGPTPRCPTPN1 | |
| SCHEMBL9403761 | 0.82 | LMNA (0.68) | FFAR1FFAR4TP53PKMRAB9A | |
| SCHEMBL6239573 | 0.82 | FFAR1 (0.76) | FFAR1FFAR4 | |
| SCHEMBL5746820 | 0.81 | MAOB (0.68) | FFAR1MAOBPKMMRGPRX4PTPN1 | |
| SCHEMBL2966035 | 0.81 | ALDH1A1 (0.66) | FFAR1FFAR4 | |
| SCHEMBL15474273 | 0.81 | FFAR1 (0.71) | FFAR1FFAR4MAOBSMN1; SMN2 | |
| SCHEMBL1746424 | 0.80 | FFAR1 (0.62) | FFAR1FFAR4PPARGPKMMRGPRX4 | |
| SCHEMBL1747052 | 0.80 | PPARG (0.81) | FFAR1FFAR4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |