Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 14/20 | 0.60 |
| ▸ | FDFT1 | P37268 | 3/20 | 0.60 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793579 | 0.80 | KDM4E (0.43) | FDPSFDFT1CA9CA12DEGS1 | |
| SCHEMBL20377227 | 0.79 | FDPS (0.51) | FDPSFDFT1 | |
| SCHEMBL7784532 | 0.77 | FDPS (0.52) | FDPSFDFT1MMP2CA9CA14 | |
| SCHEMBL7784742 | 0.77 | FDPS (0.68) | FDPSFDFT1MMP2CA9CA12 | |
| SCHEMBL15221716 | 0.76 | HCAR3 (0.50) | CA9CA14CA12DEGS1CA1 | |
| SCHEMBL4255981 | 0.76 | FDPS (1.00) | FDPSFDFT1MMP2CA9CA14 | |
| SCHEMBL8384527 | 0.76 | FDPS (0.66) | FDPSFDFT1MMP2CA9CA12 | |
| SCHEMBL15163891 | 0.76 | FDPS (1.00) | FDPSFDFT1MMP2CA9CA14 | |
| SCHEMBL15165634 | 0.75 | FDPS (1.00) | FDPSMMP2CA9CA14CA12 | |
| SCHEMBL22365607 | 0.73 | FDPS (0.62) | FDPSFDFT1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |