Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | NNMT | P40261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881081 | 0.85 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL249158 | 0.83 | NNMT (0.49) | SMN1; SMN2NNMTLMNAMAPTKDM4E | |
| SCHEMBL27639119 | 0.79 | KDM1A (0.41) | NNMTLMNAMAPTKDM4EMEN1 | |
| SCHEMBL2642344 | 0.79 | KDM1A (0.43) | NNMTLMNAMAPTKDM4EMEN1 | |
| SCHEMBL128892 | 0.79 | MEN1 (0.44) | SMN1; SMN2NNMTLMNAMAPTKDM4E | |
| SCHEMBL12649387 | 0.77 | CASP3 (0.44) | SMN1; SMN2TP53NNMTMAPTKDM4E | |
| SCHEMBL91410 | 0.76 | KDM1A (0.44) | NNMTLMNAMAPTKDM4EMEN1 | |
| SCHEMBL27943209 | 0.76 | NNMT (0.42) | SMN1; SMN2NNMTLMNAMAPTKDM4E | |
| SCHEMBL31666977 | 0.76 | TAAR1 (0.52) | CYP3A4TSHRNNMTLMNAKDM4E | |
| SCHEMBL16797049 | 0.76 | MEN1 (0.45) | SMN1; SMN2NNMTMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101193895-B | Method for producing tricyclic ketone | YAKULT HONSHA KK | 2011-06-01 | — | — | CN | claimed |
| US-8466287-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-20120041204-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2012-02-16 | — | — | US | disclosed |
| US-8067595-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2011-11-29 | — | — | US | disclosed |
| CN-101193895-B | Method for producing tricyclic ketone | YAKULT HONSHA KK | 2011-06-01 | — | — | CN | disclosed |
| US-20090023927-A1 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2009-01-22 | — | — | US | disclosed |
| CN-101193895-A | Method for producing tricyclic ketone | YAKULT HONSHA KK (JP) | 2008-06-04 | — | — | CN | disclosed |
| EP-1900740-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | Kabushiki Kaisha Yakult Honsha (JP) | 2008-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041204-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | TKT, DCK, COASY | ALDH1A1 1539/4885SMN1; SMN2 3455/4885CYP3A4 69/4885 |
| US-20090023927-A1 | Process for producing tricyclic ketone | TKT, DCK, COASY | ALDH1A1 1539/4885SMN1; SMN2 3455/4885CYP3A4 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.