Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236229 | 0.86 | GPR119 (0.50) | GPR119EPHX1 | |
| SCHEMBL6240664 | 0.85 | ALOX5 (0.49) | GPR119EPHX1ALOX5PDE4ANPC1 | |
| SCHEMBL10156216 | 0.78 | IDH1 (0.52) | EPHX1NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL12197154 | 0.74 | IDH1 (0.47) | EPHX1NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL25650188 | 0.72 | GPR119 (0.45) | GPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL24851282 | 0.72 | GPR119 (0.47) | GPR119SMARCA2SMARCA4PBRM1ABCB1 | |
| SCHEMBL30162002 | 0.72 | GPR119 (0.47) | GPR119SMARCA2SMARCA4PBRM1ABCB1 | |
| SCHEMBL1409412 | 0.72 | ADORA2A (0.37) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL3778056 | 0.72 | ALDH1A1 (0.54) | GPR119EPHX1NPC1ALDH1A1MAPT | |
| SCHEMBL30605602 | 0.72 | USP30 (0.50) | EPHX1NPC1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |