Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239442 | 0.86 | POLB (0.41) | POLBMAPK1ITGA4ITGB7HIF1A | |
| SCHEMBL2229634 | 0.86 | POLB (0.41) | POLBMAPK1ITGA4ITGB7HIF1A | |
| SCHEMBL26991038 | 0.80 | POLB (0.57) | POLBMAPK1MAPTLMNAHIF1A | |
| SCHEMBL6234635 | 0.78 | POLB (0.58) | POLBMAPK1TP53ITGA4ITGB7 | |
| SCHEMBL7345574 | 0.78 | KDM4E (0.43) | POLBTP53LMNAPDCD1CD274 | |
| SCHEMBL6238689 | 0.78 | PDCD1 (0.44) | POLBMAPK1MAPTITGA4ITGB7 | |
| SCHEMBL3337001 | 0.78 | SMN1; SMN2 (0.35) | MAPTTP53LMNATHRBCYP1A2 | |
| SCHEMBL19123170 | 0.78 | SMN1; SMN2 (0.35) | MAPTTP53LMNATHRBCYP1A2 | |
| SCHEMBL13246853 | 0.78 | SMN1; SMN2 (0.35) | MAPTTP53LMNATHRBCYP1A2 | |
| SCHEMBL6240992 | 0.78 | ITGB2 (0.46) | CYP1A2PDCD1CD274SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955046-B1 | Amino acid derivatives as anti-inflammatory agents | AJINOMOTO KK (JP) | 2005-06-22 | — | — | EP | claimed |
| EP-0955046-B1 | Amino acid derivatives as anti-inflammatory agents | AJINOMOTO KK (JP) | 2005-06-22 | — | — | EP | disclosed |
| US-6552061-B1 | For therapy and prophylaxis of inflammatory skin injuries or diseases | AJINOMOTO CO., INC. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0955046-A2 | Amino acid derivatives and anti-inflammatory agents | Ajinomoto Co., Inc. (JP) | 1999-11-10 | — | — | EP | disclosed |