Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.37 |
| ▸ | ITGAL | P20701 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239442 | 0.87 | POLB (0.41) | KDM4EHPGDALDH1A1GAAPOLB | |
| SCHEMBL2229634 | 0.87 | POLB (0.41) | KDM4EHPGDALDH1A1GAAPOLB | |
| SCHEMBL1643961 | 0.84 | GAA (0.40) | ALDH1A1GAAPOLB | |
| SCHEMBL466340 | 0.84 | GAA (0.40) | ALDH1A1GAAPOLB | |
| SCHEMBL466341 | 0.84 | GAA (0.40) | ALDH1A1GAAPOLB | |
| SCHEMBL3856794 | 0.83 | ITGA4 (0.39) | KDM4EHPGDALDH1A1PPARGGAA | |
| SCHEMBL3856786 | 0.83 | ITGA4 (0.39) | KDM4EHPGDALDH1A1PPARGGAA | |
| SCHEMBL31711243 | 0.82 | ALDH1A1 (0.46) | KDM4EALDH1A1KMT2APOLBL3MBTL1 | |
| SCHEMBL28558505 | 0.82 | CPB2 (0.38) | ALDH1A1 | |
| SCHEMBL147911 | 0.82 | CPB2 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989004835-A1 | HUMAN RESPIRATORY SYNCYTIALVIRUS VACCINE DERIVED FROM THE 1A (9.5 kD) PROTEIN | THE UPJOHN COMPANY (US) | 1989-06-01 | — | — | WO | disclosed |