Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229634 | 1.00 | POLB (0.41) | POLBMAPK1GAAHIF1ACYP2D6 | |
| SCHEMBL2980934 | 0.88 | CPB2 (0.38) | AKR1B1CPB2CPB1 | |
| SCHEMBL7345574 | 0.87 | KDM4E (0.43) | POLBGAAALDH1A1HPGDKDM4E | |
| SCHEMBL6240988 | 0.86 | POLB (0.38) | POLBMAPK1GAAHIF1AKDM4E | |
| SCHEMBL466340 | 0.85 | GAA (0.40) | POLBGAAALDH1A1 | |
| SCHEMBL466341 | 0.85 | GAA (0.40) | POLBGAAALDH1A1 | |
| SCHEMBL1643961 | 0.85 | GAA (0.40) | POLBGAAALDH1A1 | |
| SCHEMBL31711243 | 0.83 | ALDH1A1 (0.46) | POLBALDH1A1KDM4E | |
| SCHEMBL28558505 | 0.83 | CPB2 (0.38) | ALDH1A1CPB2CPB1 | |
| SCHEMBL147911 | 0.83 | CPB2 (0.38) | ALDH1A1CPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955046-B1 | Amino acid derivatives as anti-inflammatory agents | AJINOMOTO KK (JP) | 2005-06-22 | — | — | EP | claimed |
| EP-0629606-B1 | AMINO ACID DERIVATIVE AND ANTI-ACTIVE-OXYGEN AGENT | AJINOMOTO KK (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-5594012-A | OXIDATION RESISTANCE | AJINOMOTO CO., INC. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0629606-A1 | AMINO ACID DERIVATIVE AND ANTI-ACTIVE-OXYGEN AGENT | Ajinomoto Co., Inc. (JP) | 1994-12-21 | — | — | EP | disclosed |