SCHEMBL624243

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL624464	0.90	KMT2A (0.54)	GAAMAPK1MEN1KMT2AMAPT
	SCHEMBL624736	0.90	ENPP2 (0.53)	GAAMAPK1MEN1KMT2AMAPT
	SCHEMBL623279	0.89	SMN1; SMN2 (0.48)	GAAMAPK1MAPTALDH1A1LMNA
	SCHEMBL623125	0.85	SMN1; SMN2 (0.43)	MAPK1MEN1KMT2AMAPTALDH1A1
	SCHEMBL623124	0.84	MAPT (0.44)	GAAMAPK1KMT2AMAPTALDH1A1
	SCHEMBL622519	0.84	ALDH1A1 (0.51)	MAPK1MEN1KMT2AMAPTALDH1A1
	SCHEMBL624197	0.83	GHSR (0.42)	MEN1KMT2AMAPTALDH1A1LMNA
	SCHEMBL623269	0.83	MEN1 (0.46)	GAAMEN1KMT2AMAPTALDH1A1
	SCHEMBL624233	0.81	MAPT (0.45)	GAAMAPK1MEN1KMT2AMAPT
	SCHEMBL622716	0.80	NPC1 (0.53)	GAAMAPK1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.