SCHEMBL6242574

SCHEMBL6242574

CCOC(OCC)c1cccc(O)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA12 O43570 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43
TRPA1 O75762 2/20 0.42
ATM Q13315 1/20 0.42
TSHR P16473 2/20 0.41
MAPT P10636 3/20 0.36
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
BCHE P06276 2/20 0.36
ACHE P22303 2/20 0.36
TYR P14679 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
PTPN2 P17706 1/20 0.34
PTPN1 P18031 1/20 0.34
HPGD P15428 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2219505 0.84 TSHR (0.44) CA1CA2CA12CA7CA9
SCHEMBL5384908 0.83 SCN5A (0.34) CA1CA2CA12CA7CA9
SCHEMBL5383313 0.83 BCHE (0.47) CA1CA2CA12CA7CA9
SCHEMBL5380106 0.82 TSHR (0.55) CA1CA2CA12CA7CA9
SCHEMBL6238347 0.80 TSHR (0.40) CA1CA2CA12CA7CA9
SCHEMBL15048534 0.79 TRPA1 (0.46) CA1CA2CA12CA7CA9
SCHEMBL5388644 0.76 CA2 (0.44) CA1CA2CA12CA7CA9
SCHEMBL23202747 0.75 TSHR (0.50) CA1CA2CA12CA7CA9
SCHEMBL6238001 0.74 ACHE (0.46) TRPA1ATMMAPTACHELMNA
SCHEMBL17748248 0.74 GABRA1 (0.43) CA1CA2TSHRGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1534227-A1 AGENTS USED FOR DYEING KERATINOUS FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2005-06-01 EP disclosed
WO-2004022016-A1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-03-18 WO disclosed