Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | FBP1 | P09467 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243038 | 1.00 | MEN1 (0.55) | MEN1KMT2AFBP1MAPK1ALDH1A1 | |
| SCHEMBL3232414 | 0.91 | FBP1 (0.56) | MEN1KMT2AFBP1MAPK1ALDH1A1 | |
| SCHEMBL3232417 | 0.91 | FBP1 (0.56) | MEN1KMT2AFBP1MAPK1ALDH1A1 | |
| SCHEMBL6954094 | 0.78 | FBP1 (0.61) | MEN1KMT2AFBP1MAPK1ALDH1A1 | |
| SCHEMBL31380626 | 0.77 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL31380601 | 0.77 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL31380590 | 0.77 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL31380620 | 0.77 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL9850705 | 0.77 | FBP1 (0.59) | MEN1KMT2AFBP1MAPK1ALDH1A1 | |
| SCHEMBL3219973 | 0.77 | MEN1 (0.63) | MEN1KMT2AFBP1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56034654-A | — | — | None | — | — | JP | disclosed |
| WO-2005011661-A1 | PHARMACEUTICAL AGENTS | UNIVERSITY COLLEGE LONDON (GB) | 2005-02-10 | — | — | WO | disclosed |
| JP-S5634654-A | PREPARATION OF C2N+3 CYCLOALK A -N-EN-1-ONE | OGAWA HARU | 1981-04-06 | — | — | JP | disclosed |