Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3679181 | 0.85 | SGMS2 (0.60) | SGMS2NPC1HTTMEN1KMT2A | |
| SCHEMBL30194507 | 0.83 | SGMS2 (0.59) | SGMS2NPC1HTTMEN1KMT2A | |
| SCHEMBL4944383 | 0.83 | NPC1 (0.60) | SGMS2NPC1HTTMEN1KMT2A | |
| SCHEMBL6562177 | 0.83 | HTT (0.60) | SGMS2NPC1HTTMEN1KMT2A | |
| SCHEMBL19156329 | 0.83 | SGMS2 (0.59) | SGMS2NPC1HTTMEN1KMT2A | |
| SCHEMBL6243854 | 0.83 | NPC1 (0.64) | SGMS2NPC1HTTMEN1KMT2A | |
| SCHEMBL4431127 | 0.83 | SGMS2 (0.59) | SGMS2NPC1HTTMEN1KMT2A | |
| SCHEMBL14339650 | 0.83 | SGMS2 (0.59) | SGMS2NPC1HTTMEN1KMT2A | |
| SCHEMBL2999130 | 0.83 | SGMS2 (0.59) | SGMS2NPC1HTTMEN1KMT2A | |
| SCHEMBL11803091 | 0.83 | MEN1 (0.53) | NPC1MEN1KMT2AFOLH1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072759-A | Novel benzylalcohol derivatives as antidiabetics and cardiotonics | TANABE SEIYAKU CO., LTD. (JA) | 1978-02-07 | — | — | US | disclosed |
| US-4032575-A | BENZYLALCOHOL AMINE DERIVATIVES | TANABE SEIYAKU CO., LTD. (JA) | 1977-06-28 | — | — | US | disclosed |