Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872212 | 0.81 | MAOB (0.41) | MAOBL3MBTL1 | |
| SCHEMBL3678084 | 0.80 | MAOB (0.42) | MAOBKMT2AKDM4EL3MBTL1 | |
| SCHEMBL3679530 | 0.78 | L3MBTL1 (0.45) | MAOBKMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL5871986 | 0.78 | RXRA (0.36) | KMT2AIDO1 | |
| SCHEMBL498618 | 0.78 | KMT2A (0.53) | KMT2AALDH1A1 | |
| SCHEMBL5872082 | 0.77 | SMN1; SMN2 (0.46) | KMT2AALDH1A1 | |
| SCHEMBL28620558 | 0.77 | KIF11 (0.51) | KIF11MAOBKMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28137731 | 0.76 | KIF11 (0.54) | KIF11MAOBKMT2AL3MBTL1IDO1 | |
| SCHEMBL10988326 | 0.75 | KIF11 (0.50) | KIF11MAOBKMT2AKDM4EALDH1A1 | |
| SCHEMBL28750669 | 0.75 | KIF11 (0.50) | KIF11MAOBKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173160-B1 | (E)-STYRYL SULFONE ANTICANCER AGENTS | UNIV TEMPLE (US) | 2005-06-22 | — | — | EP | claimed |
| US-6787667-B2 | POLYSULFONSTYRENE POLYMER | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2004-09-07 | — | — | US | claimed |
| EP-1173160-B1 | (E)-STYRYL SULFONE ANTICANCER AGENTS | UNIV TEMPLE (US) | 2005-06-22 | — | — | EP | disclosed |