Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 12/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623995 | 0.96 | PIM1 (0.44) | PIM1DYRK1AKCNH2RET | |
| SCHEMBL625511 | 0.92 | PIM1 (0.45) | PIM1DYRK1AKCNH2 | |
| SCHEMBL624528 | 0.86 | CYP3A4 (0.41) | TSHRCYP3A4MEN1USP2KMT2A | |
| SCHEMBL626627 | 0.85 | PIM1 (0.45) | PIM1DYRK1AKCNH2CYP3A4USP2 | |
| SCHEMBL625495 | 0.82 | PIM1 (0.46) | PIM1KCNH2RET | |
| SCHEMBL625741 | 0.82 | PIM1 (0.45) | PIM1DYRK1A | |
| SCHEMBL623996 | 0.82 | THRB (0.42) | PIM1RET | |
| SCHEMBL623206 | 0.82 | PIM1 (0.47) | PIM1DYRK1AKCNH2 | |
| SCHEMBL626122 | 0.81 | PIK3CA (0.45) | PIM1KCNH2RET | |
| SCHEMBL627421 | 0.79 | RET (0.44) | TSHRCYP3A4USP2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |