Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 12/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625511 | 0.85 | PIM1 (0.45) | PIM1DYRK1AFYN | |
| SCHEMBL625742 | 0.84 | THRB (0.43) | PIM1USP30 | |
| SCHEMBL623995 | 0.84 | PIM1 (0.44) | PIM1DYRK1AFYN | |
| SCHEMBL625743 | 0.83 | PIM1 (0.42) | PIM1DYRK1AFYN | |
| SCHEMBL623866 | 0.82 | DYRK1A (0.48) | PIM1DYRK1A | |
| SCHEMBL624527 | 0.82 | PIM1 (0.43) | PIM1DYRK1A | |
| SCHEMBL624016 | 0.80 | PIM1 (0.49) | PIM1 | |
| SCHEMBL627308 | 0.79 | PIK3CA (0.49) | USP30 | |
| SCHEMBL623872 | 0.79 | FYN (0.52) | PIM1FYN | |
| SCHEMBL625034 | 0.79 | PIM1 (0.54) | PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |