Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 3/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709996 | 0.84 | ALDH1A1 (0.50) | BCL2L1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8526461 | 0.84 | ALDH1A1 (0.50) | BCL2L1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL17593363 | 0.83 | MKNK1 (0.46) | RIPK1MKNK1MKNK2NPC1RAB9A | |
| SCHEMBL14712123 | 0.83 | MEN1 (0.40) | MKNK1MKNK2NPC1RAB9AALDH1A1 | |
| SCHEMBL8855211 | 0.83 | TDP1 (0.47) | MKNK1MKNK2NPC1RAB9AMAPT | |
| SCHEMBL2592408 | 0.81 | TDP1 (0.44) | ABL1RIPK1ALDH1A1MAPT | |
| SCHEMBL3720609 | 0.81 | PTGS2 (0.51) | ABL1ABCB1BCRRPS6KA3RIPK1 | |
| SCHEMBL6871603 | 0.80 | CAMKK2 (0.56) | BCL2L1MKNK1MKNK2NPC1RAB9A | |
| SCHEMBL624668 | 0.79 | MKNK1 (0.64) | ABL1ABCB1BCRRPS6KA3USP7 | |
| SCHEMBL22230633 | 0.79 | DHODH (0.47) | ABL1ABCB1BCRRPS6KA3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524060-B2 | Therapeutic contact lens for pseudo-aphakic eyes and/or eyes with retinal neuro-degeneration | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2009-04-28 | — | — | US | claimed |