SCHEMBL6247191

SCHEMBL6247191

Cc1[nH]c(=O)cc(O)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.41
ALDH1A1 P00352 5/20 0.41
ACHE P22303 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
LMNA P02545 1/20 0.39
CA1 P00915 1/20 0.39
HPGD P15428 5/20 0.39
GAA P10253 2/20 0.38
GLA P06280 2/20 0.38
UPP1 Q16831 1/20 0.38
CYP1A2 P05177 1/20 0.38
SHMT2 P34897 1/20 0.38
HTT P42858 1/20 0.37
HSD17B10 Q99714 3/20 0.37
ERN1 O75460 1/20 0.37
LPO P22079 1/20 0.37
PTGS1 P23219 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
BAZ2B Q9UIF8 1/20 0.37
KDM5A P29375 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2333736 0.77 L3MBTL1 (0.57) KDM4EALDH1A1ACHEL3MBTL1LMNA
Hydrochloric Acid SCHEMBL6095500 0.76 L3MBTL1 (0.56) KDM4EALDH1A1ACHEL3MBTL1LMNA
SCHEMBL4928504 0.75 KDM4E (0.47) KDM4EALDH1A1LMNACA1HPGD
SCHEMBL6024645 0.74 KDM4E (0.43) KDM4EALDH1A1L3MBTL1LMNASHMT2
Hydrochloric Acid SCHEMBL4304760 0.74 L3MBTL1 (0.54) KDM4EALDH1A1ACHEL3MBTL1LMNA
SCHEMBL6024686 0.74 ERN1 (0.51) KDM4EALDH1A1L3MBTL1LMNACA1
SCHEMBL16965192 0.73 UPP1 (0.58) KDM4EALDH1A1L3MBTL1LMNAHPGD
SCHEMBL18081923 0.71 ALDH1A1 (0.41) KDM4EALDH1A1LMNACA1GAA
SCHEMBL590303 0.71 ALDH1A1 (0.41) KDM4EALDH1A1LMNACA1HPGD
SCHEMBL1326868 0.68 KDM4E (0.62) KDM4EALDH1A1L3MBTL1LMNACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820211-A Synthesis method of 4-hydroxy-5, 6-dimethylpyridine-2 (1H) -one 上海毕得医药科技股份有限公司 2024-04-05 CN claimed
US-20260125389-A1 MEMBRANE-ASSOCIATED TYROSINE AND THREONINE KINASE INHIBITOR AND USE THEREOF HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO LTD (CN) 2026-05-07 US disclosed
CN-119894902-A Membrane associated tyrosine and threonine kinase inhibitors and uses thereof 海南先声再明医药股份有限公司 2025-04-25 CN disclosed
CN-117820211-A Synthesis method of 4-hydroxy-5, 6-dimethylpyridine-2 (1H) -one 上海毕得医药科技股份有限公司 2024-04-05 CN disclosed
CN-117820211-A Synthesis method of 4-hydroxy-5, 6-dimethylpyridine-2 (1H) -one 上海毕得医药科技股份有限公司 2024-04-05 CN disclosed
CN-117820211-A Synthesis method of 4-hydroxy-5, 6-dimethylpyridine-2 (1H) -one 上海毕得医药科技股份有限公司 2024-04-05 CN disclosed
EP-1511746-A2 PROCESS FOR IMIDAZO[4,5-C]PYRIDIN-4-AMINES 3M Innovative Properties Company (US) 2005-03-09 EP disclosed
US-6743920-B2 CHORINATION REPLACING HYDROXYL GROUPS OF 2,4-DIHYROXY-3-NITROPYRIDINE DERIVATIVE; AMINATION, HYDROXYARYLATION, REDUCTION AND CYCLIZATION; AMINE REPLACEMENT OF PHENOXY FUNCTIONALITY 3M INNOVATIVE PROPERTIES COMPANY 2004-06-01 US disclosed
US-20030232852-A1 Process for imidazo[4,5-c]pyridin-4-amines 3M INNOVATIVE PROPERTIES COMPANY 2003-12-18 US disclosed
WO-2003101949-A2 PROCESS FOR IMIDAZO[4,5-C]PYRIDIN-4-AMINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232852-A1 Process for imidazo[4,5-c]pyridin-4-amines CPNE4, HTR4, IL4 KDM4E 136/4885ALDH1A1 2377/4885ACHE 1268/4885
US-20260125389-A1 MEMBRANE-ASSOCIATED TYROSINE AND THREONINE KINASE INHIBITOR AND USE THEREOF PKMYT1, PKN1, ROS1 KDM4E 1448/4885ALDH1A1 4554/4885ACHE 4882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.