Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 14/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.73 |
| ▸ | LMNA | P02545 | 8/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247200 | 0.88 | CYP1A2 (0.73) | TSHRALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL15837498 | 0.83 | TSHR (0.74) | TSHRALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL5025892 | 0.81 | LMNA (0.66) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9671587 | 0.74 | PDE7A (0.69) | TSHRALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL18029436 | 0.74 | TDP1 (0.63) | TSHRALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL22720191 | 0.73 | ALDH1A1 (0.65) | TSHRALDH1A1LMNAHSD17B10ALOX15 | |
| Iodide SCHEMBL2722495 | 0.72 | CA12 (0.57) | TSHRALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL30774061 | 0.72 | L3MBTL1 (0.75) | TSHRALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL19487245 | 0.71 | LMNA (0.77) | TSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10288927 | 0.71 | CA12 (0.58) | TSHRALDH1A1LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |