Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 10/20 | 0.48 |
| ▸ | PPARA | Q07869 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967037 | 0.83 | KDR (0.53) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL10372016 | 0.82 | FFAR1 (0.65) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL9721982 | 0.82 | KDR (0.71) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL6248263 | 0.81 | KDR (0.63) | KDRFFAR1PPARGPPARAMAPT | |
| Methane SCHEMBL7559602 | 0.79 | KDR (0.67) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL8824949 | 0.78 | KDR (0.46) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL7559600 | 0.77 | KDR (0.83) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL7564833 | 0.77 | KDR (0.65) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL19392906 | 0.77 | FFAR1 (0.68) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL6968832 | 0.77 | PPARG (0.53) | KDRFFAR1PPARGPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5693651-A | HYPOGLYCEMIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |