Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.64 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1579901 | 0.78 | ADORA2A (0.51) | CSNK1A1CLK4ADORA2AADORA1TP53 | |
| SCHEMBL3356613 | 0.78 | CSNK1A1 (0.55) | CSNK1A1CLK4ADORA2AADORA1TP53 | |
| SCHEMBL28939398 | 0.78 | CSNK1A1 (0.60) | CSNK1A1CLK4ADORA2AADORA1TP53 | |
| SCHEMBL584580 | 0.78 | CSNK1A1 (0.60) | CSNK1A1CLK4ADORA2AADORA1TP53 | |
| SCHEMBL1143429 | 0.78 | CSNK1A1 (1.00) | CSNK1A1CLK4ADORA2AADORA1TP53 | |
| SCHEMBL31492947 | 0.78 | CSNK1A1 (0.60) | CSNK1A1CLK4ADORA2AADORA1TP53 | |
| SCHEMBL1143690 | 0.78 | CSNK1A1 (0.60) | CSNK1A1CLK4ADORA2AADORA1TP53 | |
| SCHEMBL19837459 | 0.78 | CSNK1A1 (0.60) | CSNK1A1CLK4ADORA2AADORA1TP53 | |
| SCHEMBL14757551 | 0.78 | ADORA2A (0.51) | CSNK1A1CLK4ADORA2AADORA1TP53 | |
| SCHEMBL23270231 | 0.77 | P2RX3 (0.42) | CSNK1A1CLK4ADORA2AADORA1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122006472-A | Preparation method of chlorine-resistant nanofiltration membrane and chlorine-resistant nanofiltration membrane prepared by preparation method | 沃顿科技股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-106915735-B | Preparation method of nitrogen or metal doped carbon material | 广西大学 | 2020-08-11 | — | — | CN | claimed |
| CN-106960729-B | Preparation method of nitrogen-sulfur co-doped carbon material | 广西大学 | 2020-07-31 | — | — | CN | claimed |
| CN-106960729-A | A kind of preparation method of nitrogen sulphur codope carbon material | 广西大学 | 2017-07-18 | — | — | CN | claimed |
| CN-1128024-A | Process for preparing substituted 4, 6-diamino-5-cyanopyrimidines | CIBA GEIGY AG (CH) | 1996-07-31 | — | — | CN | claimed |
| CN-122006472-A | Preparation method of chlorine-resistant nanofiltration membrane and chlorine-resistant nanofiltration membrane prepared by preparation method | 沃顿科技股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-12421187-B2 | Dihydrofolate synthase (DHFS) inhibiting agents and methods of making and using same | WASHINGTON UNIVERISTY (US) | 2025-09-23 | — | — | US | disclosed |
| US-20230322667-A1 | DIHYDROFOLATE SYNTHASE (DHFS) INHIBITING AGENTS AND METHODS OF MAKING AND USING SAME | WASHINGTON UNIVERSITY (US) | 2023-10-12 | — | — | US | disclosed |
| US-11021467-B2 | Phosphatidylinositol 3-kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| CN-106915735-B | Preparation method of nitrogen or metal doped carbon material | 广西大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-106960729-B | Preparation method of nitrogen-sulfur co-doped carbon material | 广西大学 | 2020-07-31 | — | — | CN | disclosed |
| CN-106938997-B | N- (4- replaces phenethyl) acetamides and application thereof | 华东理工大学 | 2019-10-11 | — | — | CN | disclosed |
| EP-0244360-B1 | SUBSTITUTED PYRIMIDINES | CIBA-GEIGY AG (CH) | 1992-08-19 | — | — | EP | disclosed |
| US-4783468-A | Insecticidal 5-pyrimidine carbonitriles | CIBA-GEIGY CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |
| US-4783468-A | Insecticidal 5-pyrimidine carbonitriles | CIBA-GEIGY CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |
| CN-87103168-A | The pyrimidines that replaces | — | 1987-12-16 | — | — | CN | disclosed |
| EP-0244360-A2 | Substituted pyrimidines | CIBA-GEIGY AG (CH) | 1987-11-04 | — | — | EP | disclosed |
| EP-0244360-A2 | Substituted pyrimidines | CIBA-GEIGY AG (CH) | 1987-11-04 | — | — | EP | disclosed |
| US-4568744-A | ANTIBACTERICIDES AND DIRUETIC INTERMEDIATES | BURROUGHS WELLCOME CO. (US) | 1986-02-04 | — | — | US | disclosed |
| US-4116958-A | ORGANIC SYNTHETIC METHODS BENZYLPYRIMIDINE DERIVATIVES | BURROUGHS WELLCOME CO. (US) | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322667-A1 | DIHYDROFOLATE SYNTHASE (DHFS) INHIBITING AGENTS AND METHODS OF MAKING AND USING SAME | DHFR, DHPS, MTHFD1 | CSNK1A1 4353/4885CLK4 4448/4885ADORA2A 3476/4885 |
| US-12421187-B2 | Dihydrofolate synthase (DHFS) inhibiting agents and methods of making and using same | DHFR, DHPS, MTHFD1 | CSNK1A1 4353/4885CLK4 4448/4885ADORA2A 3476/4885 |
| US-11021467-B2 | Phosphatidylinositol 3-kinase inhibitors | PIK3CA, PIK3C2B, PIK3CB | CSNK1A1 63/4885CLK4 449/4885ADORA2A 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.