Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836504 | 0.87 | LMNA (0.55) | SMN1; SMN2KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL4837515 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL6676998 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL8693084 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL21332805 | 0.78 | SMN1; SMN2 (0.77) | SMN1; SMN2KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL15920987 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL13495282 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL8697615 | 0.77 | ALDH1A1 (0.55) | SMN1; SMN2KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL8696906 | 0.77 | NPC1 (0.59) | SMN1; SMN2KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL3265402 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399436-B1 | OXYTOCIN AGONISTS | FERRING BV (NL) | 2005-03-16 | — | — | EP | disclosed |