Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693084 | 0.89 | ALDH1A1 (0.54) | NPC1RAB9AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL8694138 | 0.88 | ALDH1A1 (0.53) | NPC1RAB9AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL8696809 | 0.83 | ALDH1A1 (0.71) | NPC1RAB9AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL8697615 | 0.81 | ALDH1A1 (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL21332805 | 0.78 | SMN1; SMN2 (0.77) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8693962 | 0.77 | FAAH (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL13495282 | 0.77 | SMN1; SMN2 (0.61) | NPC1ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL15920987 | 0.77 | SMN1; SMN2 (0.61) | NPC1ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL174531 | 0.77 | ALDH1A1 (0.59) | RAB9AALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL6248778 | 0.77 | SMN1; SMN2 (0.51) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |