Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21538385 | 0.77 | L3MBTL1 (0.40) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL29072886 | 0.77 | MAPT (0.37) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL558551 | 0.77 | HDAC1 (0.43) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL17309636 | 0.77 | NUDT1 (0.39) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL558358 | 0.77 | CA2 (0.52) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL30117189 | 0.77 | MAPT (0.37) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL10220461 | 0.74 | CA2 (0.36) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL30939084 | 0.74 | MAPT (0.39) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL30361289 | 0.74 | ALDH1A1 (0.35) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL12963904 | 0.74 | ALDH1A1 (0.35) | MAPTALDH1A1L3MBTL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |