Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.46 |
| ▸ | RARA | P10276 | 5/20 | 0.43 |
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | RARG | P13631 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506592 | 0.83 | MAOB (0.45) | GSTP1RARARARBRARGMAOB | |
| SCHEMBL4510658 | 0.80 | RARA (0.39) | GSTP1RARARARBRARGGAA | |
| SCHEMBL7874221 | 0.78 | RARA (0.74) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7811795 | 0.76 | RARA (0.62) | RARARARBRARGMAOBRAB9A | |
| SCHEMBL6252785 | 0.72 | RARB (0.41) | RARARARBRARGRAB9APDK2 | |
| SCHEMBL29978578 | 0.70 | GSTP1 (0.71) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL197017 | 0.70 | LMNA (0.72) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL3140318 | 0.69 | GSTP1 (0.46) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL23483029 | 0.68 | LMNA (0.69) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL1096817 | 0.68 | LMNA (0.69) | GSTP1LMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565433-A2 | NOVEL LIGANDS THAT ARE ANTAGONISTS OF RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004046096-A2 | NOVEL LIGANDS THAT ARE ANTAGONISTS OF RAF RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT,S.N.C. (FR) | 2004-06-03 | — | — | WO | disclosed |