Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057742 | 0.71 | USP30 (0.32) | — | |
| SCHEMBL625875 | 0.67 | RAB9A (0.36) | NNMT | |
| SCHEMBL30907651 | 0.67 | OPRL1 (0.36) | FLT4 | |
| SCHEMBL31533689 | 0.67 | LMNA (0.43) | — | |
| SCHEMBL9942800 | 0.66 | ABL1 (0.56) | — | |
| SCHEMBL31473604 | 0.65 | NNMT (0.33) | NNMT | |
| SCHEMBL27172580 | 0.65 | NNMT (0.40) | NNMTFLT4 | |
| SCHEMBL28841914 | 0.65 | CA2 (0.32) | — | |
| SCHEMBL30161959 | 0.65 | CA2 (0.32) | — | |
| SCHEMBL622310 | 0.65 | ABL1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603216-A1 | HETEROARYLS AND USES THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012021615-A1 | HETEROARYLS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |