Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 16/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624948 | 0.83 | BRD4 (0.43) | BRD4STK17BSTK17APIK3CG | |
| SCHEMBL626773 | 0.80 | PIK3CA (0.51) | FYNSTK17BSTK17A | |
| SCHEMBL626602 | 0.79 | STK17B (0.47) | FYNBRD4STK17BSTK17A | |
| SCHEMBL625399 | 0.74 | PIK3CA (0.53) | FYN | |
| SCHEMBL626662 | 0.72 | ADORA3 (0.40) | FYNBRD4STK17BSTK17A | |
| SCHEMBL15341063 | 0.70 | STK17B (0.51) | BRD4STK17BSTK17A | |
| SCHEMBL1945371 | 0.68 | FYN (1.00) | FYN | |
| SCHEMBL626603 | 0.67 | STK17B (0.45) | BRD4STK17BSTK17A | |
| SCHEMBL1945181 | 0.66 | FYN (0.87) | FYN | |
| SCHEMBL1944739 | 0.66 | FYN (0.68) | FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |