Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253105 | 0.95 | EPHX1 (0.55) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL6251963 | 0.89 | CHRNB2 (0.47) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL6250594 | 0.82 | ACHE (0.43) | CHRNB2CHRNA4ACHE | |
| SCHEMBL9809313 | 0.81 | TSHR (0.34) | EPHX1NFKB1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL10575820 | 0.80 | EPHX1 (0.59) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL406198 | 0.79 | ALDH1A1 (0.50) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL6250767 | 0.77 | ACHE (0.46) | EPHX1CHRNB2CHRNA4ACHE | |
| SCHEMBL12172818 | 0.77 | EPHX1 (0.71) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL14577464 | 0.77 | EPHX1 (0.40) | EPHX1SMN1; SMN2ACHE | |
| SCHEMBL36408 | 0.76 | MGAM (0.39) | APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047234-A1 | METHOD FOR PRODUCING CARBAMATE GROUP-CONTAINING (METH)ACRYLIC ESTERS | Röhm GmbH & Co. KG (DE) | 2005-05-26 | — | — | WO | disclosed |