Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249673 | 0.89 | EPHX1 (0.52) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL6253105 | 0.87 | EPHX1 (0.55) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL6250293 | 0.81 | CHRNB2 (0.45) | CHRNB2CHRNA4EPHX1SMN1; SMN2ACHE | |
| SCHEMBL9403562 | 0.79 | EPHX1 (0.37) | CHRNB2CHRNA4NFKB1MAPK1EPHX1 | |
| SCHEMBL6250787 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL10592595 | 0.79 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL1696448 | 0.77 | ALDH1A1 (0.43) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL5165665 | 0.75 | ACHE (0.66) | EPHX1ACHE | |
| SCHEMBL2404913 | 0.75 | ALDH1A1 (0.35) | EPHX1APEX1 | |
| SCHEMBL16541245 | 0.75 | CHRNB2 (0.65) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762887-A | Process for preparing acrylate-functional organopolysiloxane-urethane copolymers | WACKER SILICONES CORPORATION (US) | 1988-08-09 | — | — | US | claimed |
| EP-0006705-B1 | RADIATION CURABLE SILICON RELEASE COMPOSITIONS, THEIR USE IN MAKING COATED ARTICLES AND LAMINATES AND THE ARTICLES AND LAMINATES PRODUCED THEREBY | UNION CARBIDE CORPORATION (US) | 1983-02-16 | — | — | EP | claimed |
| EP-0003741-B1 | RADIATION CURABLE PRESSURE SENSITIVE ADHESIVE AND PROCESS OF PREPARATION THEREOF | UNION CARBIDE CORPORATION (US) | 1982-12-22 | — | — | EP | claimed |
| WO-2005047234-A1 | METHOD FOR PRODUCING CARBAMATE GROUP-CONTAINING (METH)ACRYLIC ESTERS | Röhm GmbH & Co. KG (DE) | 2005-05-26 | — | — | WO | disclosed |
| EP-0274699-B1 | A PROCESS FOR PREPARING ACRYLATE-FUNCTIONAL ORGANOPOLYSILOXANE-URETHANE COPOLYMERS | WACKER-CHEMIE GMBH (DE) | 1992-07-22 | — | — | EP | disclosed |
| US-5091440-A | Acrylate- or methacrylate-functional organopolysiloxanes | WACKER SILICONES CORPORATION (US) | 1992-02-25 | — | — | US | disclosed |
| US-4762887-A | Process for preparing acrylate-functional organopolysiloxane-urethane copolymers | WACKER SILICONES CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |
| EP-0274699-A2 | A process for preparing acrylate-functional organopolysiloxane-urethane copolymers | WACKER-CHEMIE GMBH (DE) | 1988-07-20 | — | — | EP | disclosed |
| US-4647683-A | Preparing ester containing organosilicon compounds | (SWC) STAUFFER-WACKER SILICONES CORPORATION (US) | 1987-03-03 | — | — | US | disclosed |