Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997994 | 0.85 | CASP1 (0.48) | CASP1LMNAALDH1A1TDP1CA1 | |
| SCHEMBL30307015 | 0.84 | TRPV4 (0.46) | HTTHTR2ASLC6A4LMNAALDH1A1 | |
| SCHEMBL7386055 | 0.84 | TRPV4 (0.46) | HTTHTR2ASLC6A4LMNAALDH1A1 | |
| SCHEMBL926865 | 0.84 | CA12 (0.49) | CASP1HTTSLC6A4LMNAFFAR1 | |
| SCHEMBL3877575 | 0.83 | CASP1 (0.51) | CASP1HTTSMN1; SMN2HTR2ASLC6A4 | |
| SCHEMBL5682816 | 0.83 | CASP1 (0.52) | CASP1HTTHTR2ASLC6A4LMNA | |
| SCHEMBL7090900 | 0.83 | CASP1 (0.54) | CASP1HTTSMN1; SMN2HTR2ASLC6A4 | |
| SCHEMBL5682969 | 0.82 | CASP1 (0.55) | CASP1HTTHTR2ASLC6A4FFAR1 | |
| Ammonia Solution, Strong SCHEMBL7974728 | 0.81 | CASP1 (0.53) | CASP1HTTSMN1; SMN2HTR2ASLC6A4 | |
| SCHEMBL7205989 | 0.81 | TRPV4 (0.42) | CASP1LMNAALDH1A1TDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333824-B1 | TREATMENT OF SEXUAL DYSFUNCTION WITH BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-09-07 | — | — | EP | disclosed |