Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386055 | 1.00 | TRPV4 (0.46) | TRPV4HTR2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL997994 | 0.87 | CASP1 (0.48) | MAPTTDP1PGRKMT2AALDH1A1 | |
| SCHEMBL926865 | 0.86 | CA12 (0.49) | SLC6A4SLC6A2SLC6A3HTTMAPT | |
| SCHEMBL6425430 | 0.84 | TRPV4 (0.45) | TRPV4MAPTPGRLMNA | |
| SCHEMBL6249693 | 0.84 | CASP1 (0.51) | TRPV4HTR2ASLC6A4HTTTDP1 | |
| SCHEMBL5682816 | 0.84 | CASP1 (0.52) | HTR2ASLC6A4HTTTDP1PGR | |
| SCHEMBL7450024 | 0.84 | HTR2A (0.47) | HTR2ASLC6A4SLC6A2SLC6A3HTT | |
| SCHEMBL10865382 | 0.84 | PTGES2 (0.57) | HTR2ASLC6A4SLC6A2SLC6A3HTT | |
| SCHEMBL5682969 | 0.83 | CASP1 (0.55) | TRPV4HTR2ASLC6A4HTTPGR | |
| SCHEMBL7205989 | 0.82 | TRPV4 (0.42) | TRPV4MAPTTDP1PGRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563235-B | Synthetic method of 3- (halogenated phenoxy) benzenesulfonyl chloride derivative | 上海毕得医药科技股份有限公司 | 2023-04-11 | — | — | CN | disclosed |