Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2435688 | 0.84 | ALDH1A1 (0.54) | CA1CA2ALDH1A1MAPTKDM4E | |
| SCHEMBL23886177 | 0.79 | MAPK1 (0.48) | CA2L3MBTL1CYP2C19USP2ALDH1A1 | |
| SCHEMBL23886180 | 0.79 | MAPK1 (0.48) | CA2L3MBTL1CYP2C19USP2ALDH1A1 | |
| SCHEMBL2877980 | 0.77 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| Hydrochloric Acid SCHEMBL23722066 | 0.76 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL30091889 | 0.76 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL14795443 | 0.75 | L3MBTL1 (0.50) | CA1CA2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL28659502 | 0.74 | SLC6A3 (0.59) | CA2L3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL14795372 | 0.73 | L3MBTL1 (0.53) | CA1CA2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL1726734 | 0.73 | TSHR (0.58) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044810-A1 | GLYT2 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-05-19 | — | — | WO | claimed |
| WO-2005044810-A1 | GLYT2 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-05-19 | — | — | WO | disclosed |