Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 16/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625034 | 0.85 | PIM1 (0.54) | CKS1BSKP1SKP2PIM1 | |
| SCHEMBL624017 | 0.83 | MAPT (0.49) | THRBMAPTGAA | |
| SCHEMBL625188 | 0.80 | CKS1B (0.44) | THRBMAPTCKS1BSKP1SKP2 | |
| SCHEMBL624533 | 0.80 | PIM1 (0.53) | MAPTPIM1 | |
| SCHEMBL625512 | 0.79 | THRB (0.44) | THRBMAPTGAARXFP1PIM1 | |
| SCHEMBL13556560 | 0.79 | CKS1B (0.48) | MAPTCKS1BSKP1SKP2PIM1 | |
| SCHEMBL625742 | 0.79 | THRB (0.43) | THRBMAPTRXFP1PIM1 | |
| SCHEMBL13556558 | 0.79 | CKS1B (0.47) | CKS1BSKP1SKP2PIM1 | |
| SCHEMBL626887 | 0.78 | CKS1B (0.48) | THRBMAPTCKS1BSKP1SKP2 | |
| SCHEMBL625501 | 0.77 | PIM1 (0.43) | PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |