Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 14/20 | 0.38 |
| ▸ | HTR2B | P41595 | 13/20 | 0.38 |
| ▸ | HTR2A | P28223 | 9/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13777 | 0.81 | HTR2C (0.57) | KDM1ADRD2DRD4HTR2CHTR2B | |
| SCHEMBL13778 | 0.81 | HTR2C (0.57) | KDM1ADRD2DRD4HTR2CHTR2B | |
| SCHEMBL25254330 | 0.81 | HTR2C (0.57) | KDM1ADRD2DRD4HTR2CHTR2B | |
| SCHEMBL6251811 | 0.78 | ITGB3 (0.45) | KDM1ADRD2DRD4HTR2CHTR2B | |
| SCHEMBL27270790 | 0.78 | HTR2C (0.36) | KDM1ADRD2DRD4HTR2CHTR2B | |
| SCHEMBL6251810 | 0.77 | HTR2C (0.61) | KDM1ADRD2DRD4HTR2CHTR2B | |
| SCHEMBL15428483 | 0.75 | KDM1A (0.47) | KDM1ADRD2DRD4HTR2CHTR2B | |
| SCHEMBL6250772 | 0.71 | KDM1A (0.47) | KDM1AESR2ESR1ALDH5A1ABAT | |
| SCHEMBL1960998 | 0.70 | HTR2C (0.40) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL17346800 | 0.70 | ESR1 (0.46) | KDM1ADRD2DRD4HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051904-A2 | NOVEL PROCESSES FOR THE SYNTHESIS OF CYCLOPROPYL COMPOUNDS | PHARMACIA CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |