SCHEMBL6252916

SCHEMBL6252916

C/C(=C\CCCOC(N)=O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.40
LMNA P02545 2/20 0.40
CHRM2 P08172 2/20 0.38
CHRM4 P08173 2/20 0.38
CHRM5 P08912 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
CHRNB2 P17787 2/20 0.38
CHRNA4 P43681 2/20 0.38
HTR1A P08908 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C19 P33261 1/20 0.38
CHRNA7 P36544 1/20 0.38
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CD81 P60033 1/20 0.33
EP300 Q09472 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TBXAS1 P24557 1/20 0.32
PPARD Q03181 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6252919 1.00 ALOX15 (0.40) ALOX15LMNACHRM2CHRM4CHRM5
SCHEMBL6250935 0.95 LMNA (0.39) ALOX15LMNACHRM2CHRM4CHRM5
SCHEMBL6250929 0.95 LMNA (0.39) ALOX15LMNACHRM2CHRM4CHRM5
SCHEMBL246629 0.89 CHRM2 (0.41) ALOX15LMNACHRM2CHRM4CHRM5
SCHEMBL289046 0.89 CHRM2 (0.41) ALOX15LMNACHRM2CHRM4CHRM5
SCHEMBL9343388 0.85 ALDH1A1 (0.48) ALOX15LMNACHRM2CHRM4CHRM5
Methacrylic Acid SCHEMBL21775702 0.82 CHRM2 (0.36) ALOX15LMNACHRM2CHRM4CHRM5
SCHEMBL15389339 0.81 ATM (0.52) TSHRCD81EP300ALDH1A1TBXAS1
SCHEMBL20695626 0.80 ALOX15 (0.34) ALOX15CYP2C19CD81EP300ALDH1A1
SCHEMBL28927827 0.80 TSHR (0.33) TSHRCYP2C19CD81EP300ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005047234-A1 METHOD FOR PRODUCING CARBAMATE GROUP-CONTAINING (METH)ACRYLIC ESTERS Röhm GmbH & Co. KG (DE) 2005-05-26 WO disclosed