Methacrylic Acid

Methacrylic Acid

SCHEMBL21775702

C=C(C)C(=O)O.CC(=CCCOC(N)=O)C(=O)O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.36
CHRM4 P08173 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
CYP2C19 P33261 2/20 0.36
CHRNB2 P17787 2/20 0.36
CHRNA4 P43681 2/20 0.36
TSHR P16473 2/20 0.36
LMNA P02545 2/20 0.36
HTR1A P08908 1/20 0.36
CHRNA7 P36544 1/20 0.36
ALOX15 P16050 2/20 0.33
CYP2D6 P10635 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
CD81 P60033 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289046 0.93 CHRM2 (0.41) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL246629 0.93 CHRM2 (0.41) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6252916 0.82 ALOX15 (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6547127 0.82 THRB (0.47) CYP2C19TSHRALOX15CYP2D6TDP1
SCHEMBL6547117 0.82 THRB (0.47) CYP2C19TSHRALOX15CYP2D6TDP1
SCHEMBL6252919 0.82 ALOX15 (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
Methacrylic Acid SCHEMBL30341890 0.81 ALOX15 (0.46) CYP2C19LMNAALOX15CYP2D6THRB
SCHEMBL6250929 0.81 LMNA (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6250935 0.81 LMNA (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL14472267 0.79 CD81 (0.36) CYP2C19ALOX15CYP2D6CD81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11400026-B2 Laminate, kit, and method for producing laminate FUJIFILM CORPORATION (JP) 2022-08-02 US disclosed
WO-2020122192-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2020-06-18 WO disclosed
US-20200069531-A1 LAMINATE, KIT, AND METHOD FOR PRODUCING LAMINATE FUJIFILM CORPORATION (JP) 2020-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200069531-A1 LAMINATE, KIT, AND METHOD FOR PRODUCING LAMINATE CDH1, KIT, ITGA5 CHRM2 3216/4885CHRM4 2179/4885CHRM5 1210/4885
US-11400026-B2 Laminate, kit, and method for producing laminate CDH1, KIT, ITGA5 CHRM2 3216/4885CHRM4 2179/4885CHRM5 1210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.