Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736590 | 0.84 | LMNA (0.67) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL5002848 | 0.84 | LMNA (0.67) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL8530400 | 0.84 | LMNA (0.58) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL13055383 | 0.84 | LMNA (0.80) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL11835986 | 0.83 | RAB9A (0.52) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL485753 | 0.83 | TGM2 (0.66) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL26665217 | 0.81 | LMNA (0.58) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL2559670 | 0.81 | LMNA (0.55) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL16553601 | 0.81 | HTT (0.62) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL9115718 | 0.81 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005048715-A2 | ORGANOPHOSPHORIC COMPOUNDS AND USE THEREOF | BIOAGENCY AG (DE) | 2005-06-02 | — | — | WO | disclosed |