SCHEMBL625402

SCHEMBL625402

NCCc1ccc(C(F)(F)F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 7/20 1.00
MAOB P27338 4/20 0.84
IDO1 P14902 4/20 0.54
CYP1A2 P05177 1/20 0.50
CYP2A6 P11509 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HTR1A P08908 1/20 0.50
ADRA2A P08913 1/20 0.50
SLC6A2 P23975 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTR3A P46098 1/20 0.50
BACE1 P56817 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4369846 0.98 TAAR1 (0.95) TAAR1MAOBIDO1
Iodide SCHEMBL28689118 0.98 TAAR1 (0.95) TAAR1MAOBIDO1CYP1A2CYP2A6
Bromide SCHEMBL28801000 0.98 TAAR1 (0.95) TAAR1MAOBIDO1CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL30558891 0.92 MAOB (1.00) TAAR1MAOBIDO1
SCHEMBL2872345 0.88 TAAR1 (0.78) TAAR1MAOBIDO1
SCHEMBL31377022 0.88 TAAR1 (0.78) TAAR1MAOBIDO1CYP1A2KDM4E
Hydrochloric Acid SCHEMBL17042516 0.87 TAAR1 (0.75) TAAR1MAOBIDO1
Acetic Acid SCHEMBL29202185 0.87 TAAR1 (0.75) TAAR1MAOBIDO1
SCHEMBL2025850 0.86 TAAR1 (0.76) TAAR1MAOBIDO1
SCHEMBL7777613 0.85 TAAR1 (0.72) TAAR1MAOBLOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371337-A Metal halide perovskite nanocrystalline resistant to heat-induced fluorescence quenching, and preparation method and application thereof 华南理工大学 2025-01-28 CN claimed
CN-118513552-A Preparation process of low-agglomeration nanometer copper powder and nanometer copper powder 隆基绿能科技股份有限公司 2024-08-20 CN claimed
CN-116813497-B Amide compound and preparation method, pharmaceutical composition and application thereof 天津匠新致成科技有限公司 2023-11-14 CN claimed
CN-116444454-B N-hydroxy amidine derivative, preparation method and application thereof, and tumor immunotherapy medicament 中国医学科学院医药生物技术研究所 2023-09-12 CN claimed
CN-116444454-A N-hydroxy amidine derivative, preparation method and application thereof, and tumor immunotherapy medicament 中国医学科学院医药生物技术研究所 2023-07-18 CN claimed
CN-112457245-B Synthesis method of 7- (trifluoromethyl) isoquinoline-5-amine 苏州康润医药有限公司 2022-11-22 CN claimed
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2022-06-23 US claimed
CN-110218206-B Bisindolylmaleimide derivative and preparation method and application thereof 中国海洋大学 2022-03-04 CN claimed
CN-113214236-B Preparation method of thiophene bi-1, 3, 4-oxadiazole formamide compounds, products and application thereof 南京林业大学 2022-01-04 CN claimed
CN-112457250-A Broad-spectrum fluorescent substrate and preparation method and application thereof 上海中医药大学 2021-03-09 CN claimed
US-7763618-B2 1-Pentyl-3-{6-[4-(2-trifluoromethylbenzoyl)piperazin-1-yl]-pyridin-3-yl}urea; inhibitors of stearoyl-CoA desaturase; cardiovascular disease, diabetes, obesity, metabolic syndrome XENON PHARMACEUTICALS INC. (CA) 2010-07-27 US claimed
US-20090131447-A1 COMBINATION THERAPY XENON PHARMACEUTICALS INC. (CA) 2009-05-21 US claimed
CN-101410366-A Substituted bicyclic ring derivatives and uses thereof ASAHI KASEI PHARMA CORP (JP) 2009-04-15 CN claimed
CN-101163504-A Combination therapy XENON PHARMACEUTICALS INC (CA) 2008-04-16 CN claimed
EP-1846035-A2 COMBINATION THERAPY XENON PHARMACEUTICALS INC. (CA) 2007-10-24 EP claimed
JP-2007500716-A 2007-01-18 JP claimed
US-20060293308-A1 Pyridyl derivatives and their use as therapeutic agents XENON PHARMACEUTICALS INC. (CA) 2006-12-28 US claimed
WO-2006086445-A2 COMBINATION THERAPY XENON PHARMACEUTICALS INC. (CA) 2006-08-17 WO claimed
EP-1651605-A2 PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2006-05-03 EP claimed
WO-2005011654-A2 PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2005-02-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME HCN4, SLC46A1, FES TAAR1 4232/4885MAOB 880/4885IDO1 3820/4885
US-20060293308-A1 Pyridyl derivatives and their use as therapeutic agents PRMT9, SNRPD3, PRDX5 TAAR1 3878/4885MAOB 1532/4885IDO1 2457/4885
US-20090131447-A1 COMBINATION THERAPY SCD, SCD5, ARG1 TAAR1 2558/4885MAOB 3255/4885IDO1 1601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.