Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.78 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.59 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NCF1 | P14598 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156543 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HRH3HRH4KDM4ELMNA | |
| SCHEMBL10616916 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HRH3HRH4KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7480275 | 0.98 | ALDH1A1 (0.96) | ALDH1A1HRH3HRH4KDM4ELMNA | |
| SCHEMBL54966 | 0.98 | ALDH1A1 (0.96) | ALDH1A1HRH3HRH4KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL5529448 | 0.96 | ALDH1A1 (0.92) | ALDH1A1HRH3HRH4KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL5521932 | 0.96 | ALDH1A1 (0.92) | ALDH1A1HRH3HRH4KDM4ELMNA | |
| SCHEMBL3153045 | 0.93 | ALDH1A1 (0.88) | ALDH1A1HRH3HRH4KDM4ELMNA | |
| SCHEMBL10690328 | 0.89 | LMNA (0.80) | ALDH1A1HRH3HRH4KDM4ELMNA | |
| SCHEMBL4277270 | 0.89 | HRH3 (1.00) | ALDH1A1HRH3HRH4KDM4ECYP2D6 | |
| Hydrochloric Acid SCHEMBL7468055 | 0.86 | HRH3 (0.95) | ALDH1A1HRH3HRH4KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 835 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118892484-A | Application of 4-amino-1-benzyl piperidine in preparation of medicines for preventing and/or treating acute lung injury | 中国医学科学院药物研究所 | 2024-11-05 | — | — | CN | claimed |
| CN-118892483-A | Application of MPO enzyme inhibitor in preparation of medicine for preventing and/or treating neuroinflammatory diseases | 中国医学科学院药物研究所 | 2024-11-05 | — | — | CN | claimed |
| CN-118812777-A | Anhydride-containing sulfonyl/phosphonyl copolymer and preparation method and application thereof | 四川大学 | 2024-10-22 | — | — | CN | claimed |
| CN-118459650-A | Carboxyl-sulfonyl/phosphonyl-containing copolymer and preparation method and application thereof | 四川大学 | 2024-08-09 | — | — | CN | claimed |
| CN-118067908-B | Targeted data analysis method for non-targeted metabonomics research | 长春中医药大学 | 2024-07-05 | — | — | CN | claimed |
| CN-115160300-B | Coumarin compound, preparation method thereof and application of coumarin compound in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2024-05-31 | — | — | CN | claimed |
| CN-117624140-A | CXCR4 antagonists, methods of making and uses thereof | 杭州师范大学 | 2024-03-01 | — | — | CN | claimed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | claimed |
| CN-115160300-A | Coumarin compound, preparation method thereof and application of coumarin compound in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2022-10-11 | — | — | CN | claimed |
| EP-3666852-B1 | ETCHING SOLUTION HAVING SILICON OXIDE CORROSION INHIBITOR AND METHOD OF USING THE SAME | VERSUM MAT US LLC (US) | 2022-01-05 | — | — | EP | claimed |
| US-20080108611-A1 | SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-05-08 | — | — | US | claimed |
| US-20070265264-A1 | 5-(3-chloro-4-fluoro-phenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,6,8-tetraaza-acenaphthylene-2-carboxylic acid (3,4-dimethoxy-phenyl)-amide | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-11-15 | — | — | US | claimed |
| US-20070225309-A1 | SUBSTITUTED THIATRIAZAACENAPHTHYLENE-6-CARBONITRILE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-09-27 | — | — | US | claimed |
| WO-2007092879-A2 | SUBSTITUTED THIATRIAZAACENAPHTHYLENE-6-CARBONITRILE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-08-16 | — | — | WO | claimed |
| US-20070149484-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ZENTARIS GMBH (DE) | 2007-06-28 | — | — | US | claimed |
| WO-2007054556-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ÆTERNA ZENTARIS GMBH (DE) | 2007-05-18 | — | — | WO | claimed |
| WO-2006118749-A1 | THIA-TETRAAZAACENAPHTHYLENE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-11-09 | — | — | WO | claimed |
| US-7126006-B2 | Glycoluril core molecules for combinatorial libraries | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-10-24 | — | — | US | claimed |
| US-20050250830-A1 | Glycoluril core molecules for combinatorial libraries | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-11-10 | — | — | US | claimed |
| EP-0667562-B1 | Charge injection barrier for positive charging organic photoconductor | HEWLETT PACKARD CO (US) | 2001-03-21 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149484-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | MAP4K2, MAP3K15, MAP3K5 | ALDH1A1 3097/4885HRH3 1566/4885HRH4 1597/4885 |
| US-20070225309-A1 | SUBSTITUTED THIATRIAZAACENAPHTHYLENE-6-CARBONITRILE KINASE INHIBITORS | MAP3K11, MAP3K6, MAP4K2 | ALDH1A1 2543/4885HRH3 2500/4885HRH4 1849/4885 |
| US-20050250830-A1 | Glycoluril core molecules for combinatorial libraries | UGCG, UGDH, GLUL | ALDH1A1 490/4885HRH3 3678/4885HRH4 2764/4885 |
| US-20070265264-A1 | 5-(3-chloro-4-fluoro-phenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,6,8-tetraaza-acenaphthylene-2-carboxylic acid (3,4-dimethoxy-phenyl)-amide | ADK, MAP3K9, MAP4K5 | ALDH1A1 924/4885HRH3 1681/4885HRH4 1376/4885 |
| US-20080108611-A1 | SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS | MAP4K2, MAP3K6, MAP3K2 | ALDH1A1 1988/4885HRH3 1921/4885HRH4 1568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.