SCHEMBL6255337

SCHEMBL6255337

CC[Si]1(C)C(c2cccc(-c3ccc4ccccc4c3)n2)=C(c2ccccc2)C(c2ccccc2)=C1c1cccc(-c2ccc3ccccc3c2)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.41
CYP1B1 Q16678 1/20 0.41
RAB9A P51151 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CTRC Q99895 1/20 0.39
CYP1A2 P05177 4/20 0.37
CDC25A P30304 1/20 0.36
CDC25B P30305 1/20 0.36
CDC25C P30307 1/20 0.36
DUSP3 P51452 1/20 0.36
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
AR P10275 2/20 0.35
KDM4E B2RXH2 2/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6253399 0.88 CYP1A1 (0.42) CYP1A1CYP1B1RAB9AMEN1KMT2A
SCHEMBL6253014 0.87 RAB9A (0.52) RAB9AMEN1KMT2ACYP1A2ALDH1A1
SCHEMBL6252650 0.86 CYP1A1 (0.45) CYP1A1CYP1B1RAB9AMEN1KMT2A
SCHEMBL6254045 0.84 HSD17B1 (0.39) CYP1A1CYP1B1MEN1KMT2ACYP1A2
SCHEMBL6254190 0.82 CYP11B1 (0.40) CYP1A1CYP1B1RAB9AMEN1KMT2A
SCHEMBL6255851 0.80 CYP1A1 (0.44) CYP1A1CYP1B1RAB9AMEN1KMT2A
SCHEMBL6256111 0.79 CCR1 (0.44) RAB9AMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL6253406 0.79 ALDH1A1 (0.39) RAB9AMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL6252098 0.78 RAB9A (0.41) RAB9AMEN1KMT2ACYP1A2ALDH1A1
SCHEMBL8163083 0.77 CYP1A1 (0.40) CYP1A1CYP1B1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1143538-B1 Organic electroluminescent element containing a silacyclopentadiene derivative CHISSO CORP (JP) 2005-09-14 EP disclosed
EP-0754691-B1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORP (JP) 2003-11-19 EP disclosed
EP-1143538-A1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative Chisso Corporation (JP) 2001-10-10 EP disclosed
US-6051319-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 2000-04-18 US disclosed
US-5986121-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1999-11-16 US disclosed
EP-0754691-A2 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1997-01-22 EP disclosed