Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | APEX1 | P27695 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844291 | 0.80 | MEN1 (0.36) | MEN1KMT2AAPEX1ACHENFKB1 | |
| SCHEMBL8102533 | 0.80 | MEN1 (0.36) | MEN1KMT2AAPEX1ACHENFKB1 | |
| SCHEMBL18806384 | 0.80 | — | — | |
| SCHEMBL5948812 | 0.75 | ALDH1A1 (0.39) | SMN1; SMN2LMNATSHRDNM1 | |
| SCHEMBL20368642 | 0.75 | ALDH1A1 (0.39) | SMN1; SMN2LMNATSHRDNM1 | |
| SCHEMBL5948733 | 0.73 | OPRM1 (0.40) | LMNATSHRDNM1 | |
| SCHEMBL22986852 | 0.71 | LMNA (0.41) | LMNATSHRDNM1 | |
| SCHEMBL4797069 | 0.71 | LMNA (0.41) | LMNATSHRDNM1 | |
| SCHEMBL14840061 | 0.71 | LMNA (0.41) | LMNATSHRDNM1 | |
| SCHEMBL24990076 | 0.71 | LMNA (0.41) | LMNATSHRDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603233-A1 | VACCINE ENGINEERING | AC Immune S.A. (CH) | 2013-06-19 | — | — | EP | claimed |
| WO-2012020124-A1 | VACCINE ENGINEERING | AC IMMUNE S.A. (CH) | 2012-02-16 | — | — | WO | claimed |
| EP-3527220-A1 | VACCINE ENGINEERING | AC Immune S.A. (CH) | 2019-08-21 | — | — | EP | disclosed |
| EP-2758071-B1 | VACCINE THERAPY | AC IMMUNE SA (CH) | 2018-11-28 | — | — | EP | disclosed |
| EP-2758071-A1 | VACCINE THERAPY | AC Immune S.A. (CH) | 2014-07-30 | — | — | EP | disclosed |
| EP-2603233-A1 | VACCINE ENGINEERING | AC Immune S.A. (CH) | 2013-06-19 | — | — | EP | disclosed |
| WO-2013044147-A1 | VACCINE THERAPY | AC IMMUNE S.A. (CH) | 2013-03-28 | — | — | WO | disclosed |
| WO-2012020124-A1 | VACCINE ENGINEERING | AC IMMUNE S.A. (CH) | 2012-02-16 | — | — | WO | disclosed |