Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592012 | 0.77 | MAOA (0.42) | MAOAMAOB | |
| SCHEMBL9052322 | 0.75 | MAOA (0.39) | MAOAMAOBHRH1KCNH2HTR2B | |
| SCHEMBL2928205 | 0.72 | ALDH1A1 (0.34) | MAOAMAOBALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL753043 | 0.71 | MAOA (0.39) | MAOAMAOB | |
| SCHEMBL5181287 | 0.71 | MAOA (0.46) | MAOAMAOBHRH1KCNH2HTR2B | |
| SCHEMBL14583291 | 0.70 | NPC1 (0.42) | HRH1ADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL3074959 | 0.70 | MAOA (0.50) | MAOAMAOBALDH1A1LMNACYP1A2 | |
| SCHEMBL574574 | 0.69 | MAOA (0.48) | MAOAMAOBCYP1A2KMT2A | |
| SCHEMBL253210 | 0.68 | CYP2D6 (0.38) | MAOAMAOBKCNH2DRD2SLC6A2 | |
| SCHEMBL1491183 | 0.67 | MAOA (0.46) | MAOAMAOBALDH1A1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058330-A1 | PHOSPHORUS CONTAINING COMPOUNDS USEFUL FOR THE REGULATION OF LDL AND LP(A) LEVELS | QUATRX PHARMACEUTICALS CO. (US) | 2005-06-30 | — | — | WO | disclosed |