SCHEMBL6256397

SCHEMBL6256397

O=C(O)c1ccc2c(c1C(=O)O)-c1ccccc1-2.O=C(O)c1ccc2c(c1C(=O)O)C(=O)c1ccccc1C2=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.60
ALDH1A1 P00352 6/20 0.60
KMT2A Q03164 6/20 0.60
MEN1 O00255 5/20 0.60
MAPK1 P28482 5/20 0.60
LMNA P02545 2/20 0.60
POLB P06746 2/20 0.60
THRB P10828 2/20 0.60
RECQL P46063 2/20 0.60
L3MBTL1 Q9Y468 2/20 0.58
SMN1; SMN2 Q16637 3/20 0.56
KDM4E B2RXH2 3/20 0.56
MMP14 P50281 1/20 0.56
PKM P14618 2/20 0.52
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
TSHR P16473 1/20 0.51
CYP2C19 P33261 1/20 0.51
SOS1 Q07889 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68628 0.94 MAPT (0.68) MAPTALDH1A1KMT2AMEN1MAPK1
SCHEMBL821722 0.94 MAPT (0.66) MAPTALDH1A1KMT2AMEN1MAPK1
SCHEMBL87698 0.88 MAPT (0.52) MAPTALDH1A1KMT2AMEN1MAPK1
SCHEMBL27456684 0.88 ALDH1A1 (0.78) MAPTALDH1A1KMT2AMEN1MAPK1
Hydrochloric Acid SCHEMBL4002701 0.87 MAPT (0.50) MAPTALDH1A1KMT2AMEN1MAPK1
Hydrochloric Acid SCHEMBL11418766 0.87 MAPT (0.50) MAPTALDH1A1KMT2AMEN1MAPK1
SCHEMBL3195070 0.85 MAPT (0.53) MAPTALDH1A1KMT2AMEN1MAPK1
SCHEMBL4838944 0.81 MAPT (0.60) MAPTALDH1A1KMT2AMEN1MAPK1
SCHEMBL10782597 0.78 MYC (0.53) MAPTALDH1A1KMT2AMEN1MAPK1
SCHEMBL11411791 0.77 FTO (0.73) MAPTALDH1A1KMT2AMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1347015-B1 Resin composition and molded product DAINIPPON INK & CHEMICALS (JP) 2005-09-21 EP disclosed
US-6677406-B2 Heat resistance; impact strength; dimensional stability; molding materials DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-01-13 US disclosed
US-20030187150-A1 Resin composition and molded product DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-10-02 US disclosed
EP-1347015-A1 Resin composition and molded product DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-09-24 EP disclosed