SCHEMBL4838944

SCHEMBL4838944

O=C(O)c1ccc2c(c1C(=O)OC(=O)c1c(C(=O)O)ccc3c1C(=O)c1ccccc1C3=O)C(=O)c1ccccc1C2=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.60
MEN1 O00255 7/20 0.60
KMT2A Q03164 7/20 0.60
ALDH1A1 P00352 6/20 0.60
MAPK1 P28482 5/20 0.60
LMNA P02545 2/20 0.60
THRB P10828 2/20 0.60
RECQL P46063 2/20 0.60
POLB P06746 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.56
KDM4E B2RXH2 4/20 0.56
MMP14 P50281 1/20 0.56
MITF O75030 1/20 0.52
PKM P14618 2/20 0.52
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
TSHR P16473 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68628 0.87 MAPT (0.68) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL6256397 0.81 MAPT (0.60) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL27456684 0.81 ALDH1A1 (0.78) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL821722 0.80 MAPT (0.66) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL8941340 0.79 MAPT (0.57) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL68969 0.78 MAPT (0.73) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL3195070 0.77 MAPT (0.53) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL11411791 0.77 FTO (0.73) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL2839419 0.76 MAPT (1.00) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL8635199 0.76 MAPT (0.66) MAPTMEN1KMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7390911-B2 Method for producing phthalic anhydride BASF AKTIENGESELLSCHAFT (DE) 2008-06-24 US disclosed
US-20070066836-A1 Method for producing phthalic anhydride BASF AKTIENGESELLSCHAFT (DE) 2007-03-22 US disclosed
US-4250063-A COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-02-10 US disclosed