Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.50 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31531876 | 1.00 | BCAT2 (0.53) | BCAT2IKBKBCSNK1A1TYRO3DYRK1B | |
| SCHEMBL5106250 | 0.85 | RAB9A (0.62) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7358868 | 0.85 | RAB9A (0.46) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28055770 | 0.84 | PARP1 (0.55) | BCAT2IKBKBCSNK1A1TYRO3DYRK1B | |
| SCHEMBL8913574 | 0.82 | BCAT2 (0.45) | BCAT2IKBKBCSNK1A1TYRO3DYRK1B | |
| SCHEMBL28183385 | 0.82 | IKBKB (0.47) | IKBKBNPC1RAB9APARP1MEN1 | |
| SCHEMBL15903518 | 0.82 | RAB9A (0.52) | BCAT2IKBKBNPC1RAB9APARP1 | |
| SCHEMBL31038175 | 0.81 | CNR2 (0.57) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31038178 | 0.80 | RAB9A (0.49) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28172285 | 0.79 | CNR2 (0.47) | IKBKBNPC1RAB9APARP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107162971-A | N phenyl N [8] quinolyl 4（Trifluoromethyl）The preparation method of benzamide | 湖北工业大学 | 2017-09-15 | — | — | CN | claimed |
| CN-104693355-B | Terminal-modified conjugated diene-vinyl aromatic hydrocarbon copolymer and synthesis method thereof | 奇美实业股份有限公司 | 2017-08-04 | — | — | CN | claimed |
| CN-107011263-A | The preparation method of the methoxy benzamide of N phenyl N [8] quinolyl 4 | 湖北工业大学 | 2017-08-04 | — | — | CN | claimed |
| CN-106977454-A | The preparation method of N phenyl N [8] quinoline yl-benzamide | 湖北工业大学 | 2017-07-25 | — | — | CN | claimed |
| CN-108329262-A | The synthetic method of N- (2- quinolyls) benzamide compound | 温州大学 | 2018-07-27 | — | — | CN | disclosed |
| CN-108203487-A | Terminal-modified conjugated diene-vinyl aromatic hydrocarbon copolymer, method for synthesizing same, rubber composition, and tire | 奇美实业股份有限公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-107417613-A | The preparation method of the methyl benzamide of N phenyl N [8] quinolyl 4 | 湖北工业大学 | 2017-12-01 | — | — | CN | disclosed |
| CN-104327046-B | Triazole N ethyl tetrahydroisoquinolicompounds compounds and its preparation method and application | 中国药科大学 | 2017-11-17 | — | — | CN | disclosed |
| CN-107162972-A | The preparation method of the trimethylbenzoyl amine of N phenyl N [8] quinolyl 2,4,6 | 湖北工业大学 | 2017-09-15 | — | — | CN | disclosed |
| CN-107162971-A | N phenyl N [8] quinolyl 4（Trifluoromethyl）The preparation method of benzamide | 湖北工业大学 | 2017-09-15 | — | — | CN | disclosed |
| CN-107162971-A | N phenyl N [8] quinolyl 4（Trifluoromethyl）The preparation method of benzamide | 湖北工业大学 | 2017-09-15 | — | — | CN | disclosed |
| CN-104693355-B | Terminal-modified conjugated diene-vinyl aromatic hydrocarbon copolymer and synthesis method thereof | 奇美实业股份有限公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-107011263-A | The preparation method of the methoxy benzamide of N phenyl N [8] quinolyl 4 | 湖北工业大学 | 2017-08-04 | — | — | CN | disclosed |
| CN-107011263-A | The preparation method of the methoxy benzamide of N phenyl N [8] quinolyl 4 | 湖北工业大学 | 2017-08-04 | — | — | CN | disclosed |
| CN-106977454-A | The preparation method of N phenyl N [8] quinoline yl-benzamide | 湖北工业大学 | 2017-07-25 | — | — | CN | disclosed |
| CN-106977454-A | The preparation method of N phenyl N [8] quinoline yl-benzamide | 湖北工业大学 | 2017-07-25 | — | — | CN | disclosed |
| CN-106977454-A | The preparation method of N phenyl N [8] quinoline yl-benzamide | 湖北工业大学 | 2017-07-25 | — | — | CN | disclosed |
| CN-104693355-A | Terminal-modified conjugated diene-vinyl aromatic hydrocarbon copolymer and synthesis method thereof | CHI MEI CORP | 2015-06-10 | — | — | CN | disclosed |
| EP-1430030-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | EP | disclosed |