Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | NCK1 | P16333 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322442 | 0.87 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10CYP1A2MEN1 | |
| SCHEMBL8690724 | 0.84 | SLC6A3 (0.53) | ALDH1A1KDM4EHSD17B10CYP1A2 | |
| SCHEMBL8326990 | 0.84 | RAB9A (0.53) | ALDH1A1KDM4EHSD17B10CYP1A2MEN1 | |
| SCHEMBL28183385 | 0.83 | IKBKB (0.47) | ALDH1A1KDM4EHSD17B10IKBKBPARP1 | |
| SCHEMBL6257294 | 0.82 | BCAT2 (0.53) | BCAT2ALDH1A1KDM4EHSD17B10CSNK1A1 | |
| SCHEMBL31531876 | 0.82 | BCAT2 (0.53) | BCAT2ALDH1A1KDM4EHSD17B10CSNK1A1 | |
| SCHEMBL13298989 | 0.77 | CYP1A2 (0.52) | NCK1BACE1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL14269751 | 0.76 | CLK1 (0.49) | NCK1BACE1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9255457 | 0.75 | CYP1A2 (0.49) | NCK1BACE1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL3529606 | 0.75 | BCAT2 (0.51) | BCAT2ALDH1A1KDM4EHSD17B10CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665881-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE, ANGIOTENSIN II ANTAGONIST | THE GREEN CROSS CORPORATION (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0569013-B1 | Quinoline compounds as angiotensin II antagonists | GREEN CROSS CORP (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0693478-A1 | Quinoline compounds | THE GREEN CROSS CORPORATION (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5478832-A | Angiotensin II antagonists; cardiovascular disorders | THE GREEN CROSS CORPORATION (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0569013-A1 | Quinoline compounds as angiotensin II antagonists | THE GREEN CROSS CORPORATION (JP) | 1993-11-10 | — | — | EP | disclosed |