Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262023 | 0.87 | MMP1 (0.33) | MMP1MMP8CA12CA1CA2 | |
| SCHEMBL6262020 | 0.83 | — | — | |
| SCHEMBL6263047 | 0.81 | SMN1; SMN2 (0.42) | CA2CTSK | |
| SCHEMBL6260997 | 0.79 | EPHX2 (0.41) | — | |
| SCHEMBL6261704 | 0.79 | — | — | |
| SCHEMBL6261898 | 0.78 | HPGD (0.43) | — | |
| SCHEMBL6262770 | 0.76 | METAP2 (0.43) | CTSK | |
| SCHEMBL6262590 | 0.76 | EPHX2 (0.45) | MMP1CA12CA1CA2MMP2 | |
| SCHEMBL6258385 | 0.75 | EPHX1 (0.55) | CA12CA1CA2CA9 | |
| SCHEMBL6260667 | 0.75 | METAP1 (0.33) | MMP1MMP8CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | claimed |
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | disclosed |