Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261898 | 0.87 | HPGD (0.43) | NPC1RAB9ACNR1ALDH1A1 | |
| SCHEMBL6263047 | 0.86 | SMN1; SMN2 (0.42) | NPC1RAB9AALDH1A1 | |
| SCHEMBL6262590 | 0.85 | EPHX2 (0.45) | EPHX2NPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL6263035 | 0.83 | CA1 (0.36) | NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL6262770 | 0.79 | METAP2 (0.43) | RAB9AKMT2A | |
| SCHEMBL6262023 | 0.79 | MMP1 (0.33) | MEN1KMT2A | |
| SCHEMBL6257451 | 0.79 | MMP1 (0.33) | — | |
| SCHEMBL6260999 | 0.78 | EPHX2 (0.40) | EPHX2TACR1NPC1RAB9AGPR119 | |
| SCHEMBL6261064 | 0.78 | EPHX2 (0.39) | EPHX2POLBMEN1ALDH1A1KMT2A | |
| SCHEMBL6258385 | 0.77 | EPHX1 (0.55) | EPHX2NPC1RAB9APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | claimed |
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | disclosed |