Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.55 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262770 | 0.87 | METAP2 (0.43) | EPHX1KMT2ARAB9A | |
| SCHEMBL6272074 | 0.81 | GAA (0.42) | LMNAMEN1KMT2ACA2CA12 | |
| SCHEMBL6261898 | 0.81 | HPGD (0.43) | EPHX1LMNAHTTNPC1MAPT | |
| SCHEMBL6260409 | 0.80 | EPHX1 (0.54) | EPHX1PRMT3LMNAMEN1HTR1E | |
| SCHEMBL6263047 | 0.80 | SMN1; SMN2 (0.42) | LMNACA2NPC1RAB9A | |
| SCHEMBL6261603 | 0.79 | BCHE (0.43) | EPHX1KMT2ARAB9ACYP1A2 | |
| SCHEMBL6262590 | 0.79 | EPHX2 (0.45) | EPHX1MEN1KMT2ACA2CA12 | |
| SCHEMBL6260997 | 0.77 | EPHX2 (0.41) | MEN1KMT2ANPC1RAB9AEPHX2 | |
| SCHEMBL6257451 | 0.75 | MMP1 (0.33) | CA2CA12CA1CA9 | |
| SCHEMBL6262023 | 0.75 | MMP1 (0.33) | MEN1KMT2ACA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | disclosed |