Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625785 | 1.00 | KMT2A (0.57) | KMT2ACYP2C9CYP1A2CYP3A4F3 | |
| SCHEMBL28575414 | 0.83 | ALDH1A1 (0.56) | KMT2ACYP1A2F3MGAMGAA | |
| SCHEMBL28575415 | 0.83 | ALDH1A1 (0.56) | KMT2ACYP1A2F3MGAMGAA | |
| SCHEMBL625589 | 0.80 | MAPK1 (0.45) | GSK3BRAB9AMIFMAOBMAOA | |
| SCHEMBL625103 | 0.80 | DYRK1A (0.60) | KMT2ACYP1A2GAAHPGDAKR1B1 | |
| SCHEMBL625104 | 0.80 | DYRK1A (0.60) | KMT2ACYP1A2GAAHPGDAKR1B1 | |
| SCHEMBL28588030 | 0.76 | KMT2A (0.58) | KMT2ACYP2C9CYP1A2CYP3A4GAA | |
| SCHEMBL28588029 | 0.76 | KMT2A (0.58) | KMT2ACYP2C9CYP1A2CYP3A4GAA | |
| SCHEMBL28915136 | 0.76 | MIF (0.49) | KMT2ACYP2C9CYP1A2CYP3A4GAA | |
| SCHEMBL28915135 | 0.76 | MIF (0.49) | KMT2ACYP2C9CYP1A2CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021692-A1 | CURCUMIN ANALOGS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-02-16 | — | — | WO | disclosed |